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The liver filters toxins through the sinusoid channels, which are lined with immune cells called Kupffer cells. These engulf the toxin, digest it and excrete it. This process is called phagocytosis. As most chemicals are relatively new it will be thousands of years before our body properly adapts to them.
Most drugs must pass through the liver, which is the primary site for drug metabolism. Once in the liver, enzymes convert prodrugs to active metabolites or convert active drugs to inactive forms. The liver’s primary mechanism for metabolizing drugs is via a specific group of cytochrome P-450 enzymes.
The liver produces bile to help break down and absorb fats. Waste products and toxins are removed through bile. Bile, incidentally, gives stool its color, Kwon says.
Abstract. The liver plays a unique role in controlling carbohydrate metabolism by maintaining glucose concentrations in a normal range. This is achieved by a tightly regulated system of enzymes and kinases regulating either glucose breakdown or synthesis in hepatocytes.
The liver plays a central role in all metabolic processes in the body. In fat metabolism the liver cells break down fats and produce energy. They also produce about 800 to 1,000 ml of bile per day.
It’s located in the upper right portion of your belly under the ribs and is responsible for functions vital to life. The liver primarily processes nutrients from food, makes bile, removes toxins from the body and builds proteins. It metabolizes many drugs. It breaks down fat and produces cholesterol.
The liver is the only solid internal organ capable of full regeneration. This means the remaining portion of your liver will grow back after surgery. As little as 30 percent of your liver can regrow to its original volume.
The liver performs essential, life-sustaining functions. While you can‘t live without a liver completely, you can live with only part of one. Many people can function well with just under half of their liver. Your liver can also grow back to full size within a matter of months.
Your liver can keep working even if part of it is damaged or removed. But if it starts to shut down completely—a condition known as liver failure—you can survive for only a day or 2 unless you get emergency treatment.
Symptoms